EBNA-1 antibody (AA 551-641) (Biotin)

Catalog No. ABIN1397596

This Rabbit Polyclonal antibody specifically detects EBNA-1 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Epstein-Barr Virus (EBV) and Virus.

Quick Overview for EBNA-1 antibody (AA 551-641) (Biotin) (ABIN1397596)

Target: EBNA-1 (Epstein-Barr Virus Nuclear Antigen-1 (EBNA-1))

Reactivity: Epstein-Barr Virus (EBV), Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EBNA-1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-EBNA-1 Antibody (Biotin)

Binding Specificity: AA 551-641

Cross-Reactivity: Virus

Cross-Reactivity (Details): Epstein Barr Virus

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from EBV Nuclear Antigen

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for EBNA-1

Target: EBNA-1 (Epstein-Barr Virus Nuclear Antigen-1 (EBNA-1))

Alternative Name: EBV Nuclear Antigen

Target Type: Viral Protein

Background:

Synonyms: EBNA1, EBNA-1, EBV nuclear antigen 1, Epstein Barr nuclear antigen 1, Epstein Barr virus, BKRF1, Epstein-Barr nuclear antigen 1, EBV nuclear antigen 1,

Background: Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.